Preclinical detection of liver fibrosis using dual-modality photoacoustic/ultrasound system
نویسندگان
چکیده
منابع مشابه
Preclinical detection of liver fibrosis using dual-modality photoacoustic/ultrasound system.
Liver fibrosis is a major cause for increasing mortality worldwide. Preclinical research using animal models is required for the discovery of new anti-fibrotic therapies, but currently relies on endpoint liver histology. In this study, we investigated a cost-effective and portable photoacoustic/ultrasound (PA/US) imaging system as a potential non-invasive alternative. Fibrosis was induced in mi...
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Microcirculation lesion is a common symptom of chronic liver diseases in the form of vasculature deformation and circulation alteration. In acute to chronic liver diseases such as biliary atresia, microcirculation lesion can have an early onset. Detection of microcirculation lesion is meaningful for studying the progression of liver disease. We have combined wide-field fluorescence microscopy a...
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Animal modeling is a crucial necessity in clinical studies of liver diseases. Authenticity of the data which are produced using this tool under different conditions and accuracy of the analyses and assessments which would be based on such data sets is completely dependent on the adoption of a standardized methodology for analyzes and assessment of these data sets. Cirrhosis and Fibrosis are amo...
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ژورنال
عنوان ژورنال: Biomedical Optics Express
سال: 2016
ISSN: 2156-7085,2156-7085
DOI: 10.1364/boe.7.005081